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Click here or scroll down to respond to this candidate1CURRICULUM VITAECandidate's Name
Date of Birth: Street Address -10-1984Current Position: Postdoctoral Research Associate, The University of North Carolina (UNC) at Chapel Hill, UNC Eshelman School of Pharmacy, Genetic Medicine Research Street Address Mobile No.: PHONE NUMBER AVAILABLEEmails: EMAIL AVAILABLE, EMAIL AVAILABLE and EMAIL AVAILABLE Work Experience:Dec. 2022-Present: Postdoctoral Research Associate, The University of North Carolina at Chapel Hill, UNC Eshelman School of Pharmacy, Genetic Medicine Research, 120 Mason Farm Road, Chapel Hill, NC 27599, USA Sep. 2021-Nov. 2022: Post-Doctoral Fellow, University of North Carolina at Greensboro, Department of Chemistry and Biochemistry, Center for Translational Biomedical Research, 600 Laureate Way, Suite 2203, Kannapolis, NC 28081, USAFeb. 2020-Aug. 2021. Postdoctoral Scholar at Academia Sinica, Institute of Chemistry, 128 Academia Road Sec. 2, Nankang, Taipei 11529, Taiwan. Nov. 2013-Aug. 2014: Assistant Professor of Organic Chemistry (Natural Product Chemistry), Department of Chemistry, Haramaya University, P.O.Box 138, Dire Dawa, Ethiopia.Courses taught for graduate students:Advanced Organic Chemistry (Chem.531), Mechanistic and Physical Organic Chemistry (Chem.532) and Natural Product Chemistry (Chem.632) Feb. 2014-Aug. 2014: Head Department of Chemistry, Haramaya University, Ethiopia. Jul. 2010-Oct. 2013: Lecturer of Organic Chemistry, Department of Chemistry, Haramaya University, P.O.Box 138, Dire Dawa, Ethiopia.Courses taught for undergraduate students:Organic Chemistry I (Chem.242), Organic Chemistry II (Chem.341), Physical Organic Chemistry (Chem.342), Fundamentals of Organic Chemistry (Chem.2041), Synthetic Organic Chemistry 2(Chem.446), Industrial Chemistry II (Chem.451), Biochemistry(Chem.452), Real Sample Analysis (Chem.422), Action Research Project(Prac.402) (Advising) and Student Project (Chem.459) (Advising). Jul. 2006-Aug. 2008: Graduate Assistant I and II, Assistant Lecturer, Department of Chemistry, Haramaya University, P.O.Box 138, Dire Dawa, Ethiopia. Courses taught for undergraduate students:Practical Organic Chemistry I (Chem.244), Practical Organic Chemistry II(Chem.343), Practical Organic Chemistry III (Chem.393), Practical Inorganic Chemistry II (Chem.414) and Practical Analytical Chemistry(Chem.224).Apr. 2011-Sep. 2012: Research Coordinator for Post Graduate Programs under the Department of Chemistry, Haramaya University, Ethiopia.Feb. 2010-Present: Member of the Chemical Society of Ethiopia. Sep. 2011-Present: Member of Pan African Chemistry Networking. Dec. 2013-Present: Member of Africa Materials Research Society. Oct. 03-06, 2012: Participated in Harmonization of Curriculum Modularization for B.Sc in Chemistry Program at national level held in Addis Ababa. Education:Sep. 2014-Jan. 2020: Ph.D. in Sustainable Chemical Science and Technology, Taiwan International Graduate Program (TIGP) at Institute of Chemistry, Academia Sinica, Taipei and in Collaboration with the Department of Applied Chemistry, National Chiao Tung University (now known as National Yang Ming Chiao Tung University), Hsinchu, Taiwan. Sep. 2008-Jul. 2010: M.Sc. in Organic Chemistry, Department of Chemistry, Haramaya University, P.O.Box 138, Dire Dawa, Ethiopia.Oct. 2006-Jul. 2007: Higher Diploma in Teacher Education, Haramaya University, Ethiopia. Sep. 2003-Jul. 2006: B.Ed. in Chemistry, Department of Chemistry, Haramaya University, Sep. 2001-Jun. 2003: Preparatory for University Education, Shire Preparatory School, Tigray, Ethiopia.Sep. 1999-Jun. 2001: General Secondary Education, Hakfen Secondary School, Selekleka, Tigray, Ethiopia.3Oral Presentation and Participation in Conferences: Jun. 14, 2024: Poster presented in the 2024 North Carolina Postdoctoral Research Symposium, North Carolina Biotechnology Center, Durham, North Carolina, US. Mar. 1, 2024: Attended the Pharmaceutical Sciences Research & Graduate Education Retreat, Friday Conference Center, Chapel Hill, North Carolina, US. Mar. 3, 2023: Attended The 2023 Eshelman School of Pharmacy & Graduate Education Research Retreat, Carolina Inn, Chapel Hill, North Carolina, US. Mar. 12-14, 2021: Ph.D. Thesis presented at the 2021 Chemistry National Meeting, National Central University, Taoyuan City, Taiwan.Dec. 08-12, 2019: Poster presented in the 18th Asian Chemical Congress and the 20th General Assembly of the Federation of Asian Chemical Societies, Taipei, Taiwan. Jun. 30-Jul. 04, 2019: Paper presented in the 20th European Carbohydrate Symposium(Eurocarb2019), Leiden, the Netherland.May 04, 2019: Paper presented in the 4th ACS Taiwan Chapter Graduate Student Conference, Taiwan National University, Department of Chemistry, Taipei, Taiwan.Apr. 24-25, 2019: Poster paper presented in the 2019 GlycoForum Retreat, Pacific Hot Spring Hotel Green Bay, Taipei, Taiwan.Dec. 07-09, 2018: Attended the Annual Meeting of Chinese Chemical Society Located in Taipei (CCSLT), Sun Yat-sen University, Taiwan.Nov. 18-21, 2018: Poster paper presented in the 10th 2018 Asian Community of Glycoscience and Glycotechnology (ACGG) Annual Conference, Tainan, Taiwan. Aug. 01-03, 2018: Attended the 2018 Frontiers in Chemical Biology Symposium, Yilan, TaiwanDec. 01-03, 2017: Poster paper presented in the Annual Meeting of Chinese Chemical Society Located in Taipei (CCSLT), Chiayi, Taiwan. Apr. 10-11, 2017: Attended Glyco-retreat symposium (Carbohydrate and glycobiology) at new Taipei city, Taiwan.Jun. 13-17, 2016: Attended the 23rd Pacific Science Congress at Academia Sinica, 128 Academia Road Sec. 2, Nankang, Taipei 115, Taiwan. Feb. 24-28, 2014: Research paper presented in the 30th annual congress of the Chemical 4Society of Ethiopia, Mekelle, Ethiopia.Nov. 24-29, 2013: Research paper presented in the 5th Pan African Chemistry Networking Congress, Addis Ababa, Ethiopia.Dec. 08-13, 2013: Research paper presented in the 7th International Africa Materials Research Society Conference, Addis Ababa, Ethiopia.Nov. 03-07, 2012: Poster paper presented in the 4th Pan African Chemistry Networking Congress, Addis Ababa, Ethiopia.Feb. 25-27, 2011: Research paper presented in the 27th annual congress of the Chemical Society of Ethiopia, Addis Ababa, Ethiopia.Professional Training:Apr. 25-26, 2024: Responsible Conduct of Research (RCR) Training for Postdoctoral Scholars(Spring 2024), UNC Toy Lounge, Dey Hall, Chapel Hill, North Carolina, US. Jun. 20-Jul. 05, 2013: Training on MATLAB organized by College of Natural and Computational Sciences (CNCS), Haramaya University, Ethiopia. May 07-18, 2013: Training on Physical Methods for Characterization of Nanomaterials (X- ray Diffraction, X-ray Spectroscopy for Elemental Analysis, TEM and SEM & Electron Spectroscopy for Surface Analysis organized by CNCS, Haramaya University, EthiopiaApr. 15-21, 2013: Training on Chemometrics and Data Analysis organized by CNCS, Haramaya University, EthiopiaDec. 2011-Jun. 2012: Attending and passing successfully French classes, School of Foreign Language Studies, College of Social Sciences and Humanities, Haramaya University, Ethiopia.Apr. 2008-Jul. 2008: Training on English Language Improvement course in Academic writing for postgraduate students, organized by School Graduate Studies, Haramaya University, Ethiopia.Awards:Mar. 12-14, 2021: Ta-shue Chou Organic Chemistry Thesis Award-Honorable Mention at the 2021 Chemistry National Meeting, National Central University, Taiwan. Feb. 18, 2020: Postdoctoral Scholar, Institute of Chemistry, Academia Sinica, 128 Academia Road Sec. 2, Nankang, Taipei 11529, Taiwan. Dec. 08-12, 2019: Best Prize Certificate in the 18th Asian Chemical Congress and 5the 20th General Assembly of the Federation of Asian Chemical Societies. Jun. 19, 2019: Taiwan International Graduate Program (TIGP) Travel Grant. Nov. 18-21, 2018: Poster award in the 10th 2018 Asian Community of Glycoscience and Glycotechnology (ACGG) Annual Conference, Tainan, Taiwan May 10, 2014: Ph.D. Scholarship in Sustainable Chemical Science and Technology (SCST), Taiwan International Graduate Program (TIGP) in Collaboration with the Department of Applied Chemistry, National Chiao Tung University (now known as National Yang Ming Chiao Tung University), Hsinchu, Taiwan. Research Interest:Antiviral Candidate's Name , K.H; Mohammad, A. H.; Peter, J. B.; Eric, M. M.; John D. S.; Sumera, P.; Kenneth. H. P.; Konstantin, I. P.; Nathaniel, J. M.; Mark, H.; Timothy, M. W.* Structure Activity of -Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Anti-alphavirus Activity. BioRxiv, 2024, 1-65. DOI: https://doi.org/10.1101/2024.06.12.5987223. Eric, M. M.; John, D. S.; Tina, M. L.; Paul, B. H.; Anirban, G.; Mohammad, A. H.; Asressu, K.H.; Peter, J. B.; Michael, A. S.; Laura, E. H.; Angie, L. M.; Thomas, S. W.; Christine, A. M.; Natalie, K. B.; Jamie, J. A.; Craig, E . C..; Daniel, N. S.; Nathaniel, J, M.; Mark, H.; Timothy, M. W.; Konstantin, I. P.; Kenneth. H. P.* Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach. BioRxiv, 2024, 1-21.DOI: https://doi.org/10.1101/2024.03.22.586341. Cited by 2 4. Anirban, G.; lvaro, F. M.; Asressu, K.H.; Anwar. H.; Matthew, H. T.; Timothy, M.W. Identification of Dihydropyrazolo[1,5-a]pyrazin-4(5H)-ones as Cyclic Products of - 6Amidomethyl Vinyl Sulfone Alphavirus Cysteine Protease Inhibitors. ChemRxiv, 2024, 1-19. DOI: 10.26434/chemrxiv-2024-wh6tp. Cited by 1 5. Asressu, K.H.; Zhang, Q.* Detection and Semi-quantification of Lipids on High- Performance Thin-Layer Chromatography Plate using Ceric Ammonium Molybdate Staining. Eur. J. Lipid Sci. Technol., 2022, 125, 2200096. Cited by 2 DOI: https://doi.org/10.1002/ejlt.2022000966. Asressu, K.H.; Chan, C. -K.; Wang, C.-C*. TMSOTf-catalyzed Synthesis of Trisubstituted Imidazoles Using Hexamethyldisilazane as a Nitrogen Source under Neat and Microwave Irradiation Conditions. RSC Adv. 2021, 11, 28061-28071. DOI: https://doi.org/10.1039/D1RA05802A Cited by 26 7. Asressu, K.H.; Chang, C.-W.; Sarah, L.; Wang, C.-C*. Donor-Reactivity-controlled Sialylation Reactions. Eur. J. Org. Chem. 2021, 4525-4530. DOI: https://doi.org/10.1002/ejoc.202100718 Cited by 9 8. Asressu, K.H.; Chan, C. -K.; Wang, C.-C*. One-pot Synthesis of 1, 5-Diketones under Transition-Metal-free Condition: Application in the Synthesis of 2,4,6-Triaryl Pyridine Derivatives. ACS Omega. 2021, 6, 7296-7311.DOI: https://doi.org/10.1021/acsomega.0c05328 Cited by 16 9. Asressu, K.H.; Wang, C.-C*. SnCl4-catalyzed Solvent Free Acetolysis of 2, 7- AnhyCandidate's Name , K.H*.; Tesfahun, K.T. Chemical and Antimicrobial Investigations on Essential Oil of Rosmarinus officinalis Leaves Grown in Ethiopia and Comparison with other Countries. J. App. Pharm. 2014, 6, 132-142.DOI: PHONE NUMBER AVAILABLE.112 Cited by 24713. Tekle, K. K.; Tesfahun, K. T.; Asressu, K.H*.; Aman, D. B. Chemical Investigation of Lawsonia inermis Leaves from Afar Region, Ethiopia. Orient. J. Chem. 2013, 29, 1129- 1134. DOI: http://www.orientjchem.org/?p=339 Cited by 35 14. Asressu, K.H*.; Aman, D. B. Chemical Composition and Antimicrobial Activity of Haramaya Propolis (Bee glue), Ethiopia. Int. J. Pharm. Sci. Res. 2013, 4, 734-740. DOI: ttp://dx.doi.org/10.13040/IJPSR.0975-8232.4(2).734-40 Cited by 11 15. Asressu, K.H*. Antimicrobial Activity and Phytochemical Screening of Crude Extracts of Medicinal Plants Grown in Eastern Ethiopia. Int. J. Pharm. Biol. Sci. 2013, 4, 326-333. Cited by 22http://www.scopus.com/inward/record.url?eid=2-s2.0-84889010555&partnerID=MN8TOARS 16. Asressu, K.H.; Tesfahun, K.T.; Aman, D. B*. A Comparative Study of Volatile Components of Propolis (Bee Glue) Collected from Haramaya University and Assela Beekeeping Centers, Ethiopia. Bull. Chem. Soc. Ethiop. 2012, 26, 353-360. DOI: http://dx.doi.org/10.4314/bcse.v26i3.4 Cited by 29 17. Asressu, K.H.; Tesfa. G.; Tasew, G. Antimicrobial Activities and Concentration of Some Metals in Rosemary. Lambert Academic Publishing, Saarbrcken, Germany. ISBN: 978- 3-659-26027-8, 2012, pp. 1-68.18. Asressu, K.H. Key Lecture Notes on Basic Organic Chemistry. Lambert Academic Publishing, Saarbrcken, Germany. ISBN: 978-3- 659-28590-5, 2012, pp. 1-284. 19. Asressu, K.H. Concise Organic Chemistry. Lambert Academic Publishing, Saarbrcken, Germany. ISBN: 978-3-659-29356-6, 2012, pp. 1-256. Technical expertise and skills:1. Data management skills such as in Signals Notebooks, Collaborative Drug Discovery(CDD) Vault and GitHub.2. Prediction of compound properties by filtering small chemical datasets for drug-like small molecules using tools and software such as stoplight, Molsoft Browser, Datawarrior, BBB Score, CNS Score, MPO Score, SMARTCyp and ChemDraw. 3. Quality control (QC) analysis of diversified samples using LC-MS to check their purity. 4. Handled various synthetic methodologies and transformations and have solid knowledge of small molecule synthesis and reaction mechanisms. 5. Capable of handling multi-step reactions from mg scale to gm scale. 86. Had experience of handling reaction in microwave-assisted organic synthesis. 7. Successfully carried temperature reactions from -78 to 160 oC. 8. Had on experience on running experiments using low temperature NMR instrument. 9. Well versed in purification techniques like Biotage flash column chromatography, Preparative-HPLC, RP LC-MS, preparative TLC and recrystallization. 10. Well versed of extraction, isolation and characterization method of new compounds from natural sources by using 1D and 2D NMR, HRMS, IR, UV and Direct Diffusion Mass. 11. Literature searching from databases such as SciFinder and Reaxys. 12. Screening antimicrobial activities of isolated products using Petri dish and Paper Disc Bioassay Methods.13. Presentation skills of results at local and international conferences and symposiums. References:1. Timothy M. Willson, Ph.D., Harold Kohn Distinguished Professor in Open Science Drug Discovery and Chief Scientist, The University of North Carolina (UNC) at Chapel Hill, UNC Eshelman School of Pharmacy, Genetic Medicine Research, 120 Mason Farm Road Campus Box 7356, Chapel Hill, NC 27599-7356Mobile No.: PHONE NUMBER AVAILABLEEmail: EMAIL AVAILABLE2. Cheng-Chung Wang (Ph.D.), Research Fellow, Academia Sinica, Institute of Chemistry,, 128 Academia Road, Section 2, Nankang, Taipei, Taiwan. Emails: EMAIL AVAILABLE and EMAIL AVAILABLE Mobile No.: PHONE NUMBER AVAILABLE3. Endale Teju Bedada (Ph.D.), Associate Professor of Analytical Chemistry, Haramaya University, Head Department of Chemistry, Ethiopia Mobile No.: PHONE NUMBER AVAILABLEEmails: EMAIL AVAILABLE and EMAIL AVAILABLE 4. Aman Dekebo Boru (Ph.D.), Professor of Chemistry, Adama Science and Technology University, Department of Applied ChemistryEmail: EMAIL AVAILABLEMobile No.: PHONE NUMBER AVAILABLE95. Mehari Muuz Weldemariam (Ph.D.), Staff Scientist at University of Maryland School of Pharmacy, 20 N Pine St, Baltimore, MD 21201 USAE-mail: EMAIL AVAILABLEMobile No.: PHONE NUMBER AVAILABLE |
