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EducationSkillsContactAddressLanguagesSummaryExperienceFull-TimeFull-TimeFull-TimeFull-TimeFull-TimeFull-TimeFull-TimeFull-TimeFull-TimeAccomplishmentsKanta OchaniSenior Clinical CoordinatorMBBS1992People Medical College, Nawabshah, PakistanB.S. (Bachelor of Science) in Biology1984Sindh University Mirpurkhas, PakistanIRB TrainingDatabase fluency (RED CAPE, CTSU,LEGACY)Proficient in Microsoft Office SuiteCompleted CITI research courses includingHuman Subjects Research, GCP, and COIMicrosurgery (All Kinds of Major and minorsurgical procedures)Drug Toxicity AssaysCell and Tissue CultureWestern BlottingElisa, Whole Blood, and Protein AssaysEMAIL AVAILABLEEMAIL AVAILABLEPhone: PHONE NUMBER AVAILABLE1 Duchess CourtDix Hills, NY 11746Fluent in: English, Sindhi, Urdu, HindiExperienced medical researcher looking for a rewarding position as a senior clinical coordinator in a high growth and high impact clinical setting Division of Kidney Diseases and HypertensionSenior Clinical Research Coordinator - Great Neck, NY October 2022 - PresentCenter for Health Innovations and Outcome Research Senior Clinical Research Coordinator,  Manhasset, ny Nov 2020 - PresentPerformed lead CRA tasks including performing monthly & quarterly monitoring for team projects, daily review of monitor compliance, and organization and leading of virtual and in-person group meetingsSchedules subjects for protocol-related evaluations. Coordinate with physicians, investigators, sponsors, and patientsCoordinating IRB applications, assist and prepare amendments and continuing review documentation as neededScreen & enroll patients into trialsObtain informed consent from subjects, perform data collection and entry, The Feinstein Institute for Medical ResearchResearch Associate  Manhasset, NYMar 2020 - Nov 2020Contributes to the publication of research papers, submitting conference proposals, and presenting at national research conferencesPerformed research within the scope of study protocols and routinely conducted femoral vein cannulation, CLP, jugular vein cannulation, and Vagus nerve stimulation using procedures such as subdiaphragmaticvagatomy within in vivo models Preparing and monitoring subjects research visits and discuss in weekly and monthly research meetings.DEPT OF RADIATION MED. AT CENTER FOR ADVANCED MEDICINE Research Coordinator  Lake Success, NYFeb 2019 - Mar 2020Managed all research related activities for the department of radiation including the development of study protocols and measures, implementations of study procedures, outreach, data collection and management, and budget development Worked within various data bases, such as Redcap, IMedidata CTSU and Legacy fluently The Feinstein Institute for Medical ResearchResearch Assistant investigator  Manhasset, NYJan 2017 - Jan 2019The Feinstein Institute for Medical ResearchPost Doc Research Fellow  Manhasset, NYJan 2003 - Jan 2017Queens Long Island Medical Group, P.CMedical assistant - Hicksville, nySept 2002 - Jan 2003Marvi General HospitalMedical officer (primary care physician) - Malti, PK Jan 1995 - Sept 1996Lyari General and Dow Medical College HospitalResident (OB/GYN) - Karachi, PKJan 1993 - Jan 1995Grand Award for Academic excellence, People's Medical College, Nawab shah, Pk1986-1991Karze Husana Prize, People's Medical CollegeNawab shah, PK1987-1990Presidential Scholarship, lbne Rashad College, Mirpurkhas, PK 1982-1984PublicationsSpyropoulos, Alex C., et al. Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-Risk Hospitalized Patients With COVID-19. JAMA Internal Medicine, no. 12, American Medical Association (AMA), Dec. 2021, p. 1612. Crossref, doi:10.1001/jamainternmed.2021.6203 Goldin, Mark, et al. Treatment-Dose LMWH versusProphylactic/Intermediate Dose Heparins in High-Risk COVID-19 Inpatients: Rationale and Design of the HEP-COVID Trial. Thrombosis and Haemostasis, no. 12, Georg Thieme Verlag KG, Apr. 2021, pp. 168495. Crossref, doi:10.1055/a-1475-2351.Perveen, Shahana, et al. Correction: MIF Inhibition Enhances Pulmonary Angiogenesis and Lung Development in Congenital Diaphragmatic Hernia. Pediatric Research, no. 5, Springer Science and Business Media LLC, Mar. 2019, pp. 735735. Crossref, doi:10.1038/sPHONE NUMBER AVAILABLE Lee JY, Linge HM, Ochani K, Lin K, Miller EJ (2016) Regulation of angiopoietin- 2 secretion from human pulmonary microvascular endothelial cells. Exp Lung Res. 2016 Sep 1:1-12.Lee JY, Linge HM, Ochani K, Lin K, Miller EJ ( 2016) N-Ethylmaleimide Sensitive Factor (NSF) Inhibition prevents vascular instability following Gram Positive pulmonary challenge. PLoS One. 2016 Jun 29;11(6):e0157837. doi: 10.137lzjoumal.pone.0157837. eCollection 2016.Linge HM, Ochani K, Lin K, Lee JY, Miller EJ ( 2015) Age-dependent alterations in the inflan1matory response to pulmonary challenge.Imrnunol Res 2015 Dec;63(1- 3):209-l 5.doi: 10.1007/sPHONE NUMBER AVAILABLE Linge HM, Lee JY, Ochani K, Koga K, Kohn N, Ojamaa K, Powell SR, Miller El (2015) Age influences inflammatory responses, hemodynamics, and cardiac Proteasome activation during acute lung in_jmy. Exp lung Res 2015 May;41(4):216- 27. doi: PHONE NUMBER AVAILABLE.999174. Epub 2015 Apr 6.Yang YM, Yuan H, Edward JG, Skayian Y, Ochani K, Miller EJ, Sehgal PB. (2015) Deletion of ATAT Sa/bin vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease. Mo!Med 2015 Mar 13;20:625-38. doi: 10.2119/molmed.2014.00180. Huston JM, Rosas-Ballina M, Xue, X, Dowling 0, Ochani K, Ochani M, Chatterjee P,Tracey KJ & Metz CN. (2009) Cholinergic neural signals to the spleendown-regulate leukocyte trafficking via CDl lb. J lmmunol 2009. Jul1;183(1):552-9.Pavlov VA, Parrish WR, Rosas-Ballina M, Ochani M, Puerta M, Ochani K, Chavan S, Al-Abed Y, Tracey KJ. (2009) Brain acetylcholinesterase activity controls Systemic cytokine levels through the cholinergic anti-inflammatory pathway Brain Behav Immun. Jan;23(1):41-5.Rosas-Ballina M, Ochani M, Parrish WR, Ochani K, Harris YT, Huston JM, Chavan S, Tracey KJ. Splenic nerve is required for cholinergic anti inflammatory Pathway control of 1NF in endotoxemia .Proc Natl Acad Sci US A. 2008 Aug 5;105(31):11008-13.Huston JM, Wang H, Ochani M, Ochani K, Rosas-Ballina M, Gallowitsch- Puerta M, Ashok M, Yang L, Tracey KJ, Yang H. (2008) Splenectomy protects against sepsis lethality and reduces serum HMGB1 levels. J Immunol. 2008 Sepl 81(5):3535-9Parrish WR, Rosas-Ballina, Gallowitsch-Puerta M, Ochani M, Ochani K, Hudson LQ, Lin X, Patel N, Jonson SM, Chavan S, Goldstein R, Czura CJ, Miller EJ, Al Abed Y Tracey KJ, Pavlov V A.(2008) Modulation of 1NF Release by Choline Requires Alpha7 Subunit Nicotinic Acetylcholine Receptor- Mediated Signaling. Mol Med. 2008 Jun 26.PMID: 18584048 ( pubMed - in Process)Huston JM, Gallowitsch-Puerta M, Ochani M, Ochani K, Yuan R, Rosas- Ballina M, Ashok M, Goldstein RS, Chavan S, Pavlov VA, Metz CN, Yang H, Czura CJ, Wang H,Tracey KJ.(2007) Trancutaneous vagus nerve stimulation reduces serum high mobility group box 1 and improves survival in murine sepsis. Crit Care Med. Dec;35(12):2762-8.Pavlov V, Ochani M, Yang LH, Gallowitsch- Puerta M, Ochani K, Lin X, Levi J, Parrish WR, Rosas-Ballina M, Czura CJ, Larosa GJ, Miller EJ Tracey KJ, Al. Abed Y.( 2007) Selective alpha7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis. Crit Care Med Apr;35(4):1139-44.Qin S, Wang H, Yuan R, Li H, Ochani M, Ochani K, Rosas-Ballina M, Czura CJ, HustonJM, Miller E, Lin X, Sherry B, Kumar A, Larosa G, Newman W, Tracey KJ, Yang H. (2006) Role of HMGB 1 in apoptosis-mediated sepsis lethality. J Exp MedJ Exp Med Jul 10;203(7):1637-42. Huston JM, Ochani M, Rosas-Ballina M, Liao H, Ochani K, Pavlov VA, Gallowitsch-Puerta M, Ashok M, Czura CJ, Foxwell B, Tracey KJ, Ulloa L.(2006) Splenectomy inactivates the cholinergic anti-inflammatory pathway during lethalendotoxemia and polymicrobial sepsis. J Exp Med Jul 10;203(7):1623-8. Pavlov V, Ochani M, Gallowitsch Pureta M, Ochani K, Huston, Czura C J, Al. Abed Y and K J Tracey.(2006) Central muscarinic cholinergic regulation of the systemic inflamrnato1y response during endotoxemia. Proc. Natl. Acad. Sci. USA 103,5219-5223.AL.Abed Y, Dabideen D, Aljabari B, Valster A, Messmer D, Ochani M, Tanovic M, Ochani K, Bacher M, Nicoletti F, Metz C, Pavlov V, Miller E J, Tracey Kl (2005) ISO-1 binding to the tautomerase active site of macrophage migration inhibit (MIF) its pro-inflammatory activity and increases survival in severe sepsis. J Biol Chem. Nov 4;280(44):36541-4. Chen G, Li J, Qiang X, Czura CJ, Ochani M, Ochani K, Ulloa L, Yang H, Tracey K J, Wang P, Sama A.E and Wang H (2005). Suppression of HMGB 1 release by stearyl lysophosphatidylcholine an additional mechanism for its therapeutic effects in experimental sepsis. Journal of Lipid Research(JLR) Vol: April 46 (4):623-627MEETING PRESENTATIONSV. A. Pavlov, M. Ochani, K. Ochani, M. Rosas-Ballina, Al-Abed and K.J.Tracey. The anti-inflammatory efficacy of xanomeline is brain muscarinic receptor mediated and long-lasting. Feinstein Institute for Medical Research North Shore - LIJ Health system 7th Annual Scientific Retreat (September, 2008). Mohonk Mountain House Lake Mohonk, New Paltz, NY. V. A. Pavlov, W. R. Parrish, M. Rosas-Ballina, M.Gallowitsch Pureta M. OchaniK. Ochani, Lin. X, Patel. N, Chavan.S, Goldstein. R, C. Czura, Miller.E, Al Abed, K. J. Tracey. Modulation ofTNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling. Thirty Ist Annual conference on Shock.M. Rosas-Ballina, M. Ochani, K. Ochani, J. Huston, R, Harris Harris YT, Goldstein. R, C. Czura, K.J. Tracey. Attenuation of systemic TNF in endotoxemia by vagus nerve stimulation requires an intact splenic nerve. Thirty Ist Annual conference on Shock.H. Wang, J. Huston, R. R.Yuan, H. Wang, M. Ochani, K. Ochani, M. Rosas Ballina, J. Ma, Li. H, and K.J. Tracey. Spleen Apoptosis is a critical determinant of HMGB1- mediated Sepsis Lethality in Mice. Feinstein Institute for Medical Research North Shore - LIJ Health system 7th Annual Scientific Retreat (September 24-25, 2007).Mohonk Mountain House Lake Mohonk, New Paltz, NYM. Rosas-Ballina, M. Ochani, K. Ochani, J. Huston, R. Goldstein, L. Ulloa, C. czura, K. J. Tracey. Vagus nerve control ofTNF production by splenic macrophages in endotoxemia. Feinstein Institute for Medical Research North Shore - LIJ Health system 7th Annual Scientific Retreat (September 24-25, 2007). Mohonk Mountain House Lake Mohonk, New Paltz, NY Harris YT, Jacob NE, Li H, M. Ochani, Chavan S, K.Ochani, W.R. Parrish, _M. Rosas-Ballina and K. J. Tracey. Rescuing Insulin Sensitivity with the Cholinergic Anti-inflammatory pathway. Feinstein Institute for Medical Research N01th Shore- LIJ Health system 7th Annual Scientific Retreat(September 24-25, 2007). Mohonk. Mountain House Lake Mohonk, New Paltz, NY.V. A. Pavlov, M. Ochani, W.R. Parrish, M. Rosas-Ballina, K. Ochani, M. Gallowitsch Pureta, C. Czura, Al-Abed, K. J. Tracey. Brain Cholinergic muscarinic anti-inflammatory pathway. Feinstein Institute for Medical Research North Shore - LIJ Health system 7th Annual Scientific Retreat(September 24-25, 2007). Mohonk. Mountain House Lake Mohonk., New Paltz, NYY. A. Levine, M. Ochani, K.Ochani, Y. Tamari & K.J.Tracey. Elevated Plasma hemoglobin in cecal ligation and puncture induced-sepsis. Thirtieth Annual conference on Shock, Baltimore, MD- June 9-12, 2007. J.H Houston, MR.Yuan, H. H. Wang, M. Ochani, K. Ochani, M. Rosas-Ballina, J. Ma, 1. Yang, K.J. Tracey & H.Yang. Spleen apoptosis is a critical detemlinant in HMGB-1 mediated sepsis letality in mice. Thirthieth Annual conference on Shock, Baltimore, MD- June 9-12, 2007. M. Rosas-Ballina, M. Ochani, K. Ochani, J. Huston, R. Goldstein, L. Ulloa, C. czura, K. J. Tracey. Vagus nerve control of TNF production by splenic macrophages in endotoxemia . Thirthieth Annual conference on Shock, Baltimore MD- June 9-12, 2007.V. A. Pavlov, M. Ochani, W.R. Parrish, M. Rosas-Ballina, K. Ochani, M. Yu, Y. Al-Abed, K. J. Tracey. The anti-inflammatory efficacy of Galantamine is dependent on the integrity of the cholinergic anti-inflammatory pathway. Thirthieth Annual conference on Shock, Baltin1ore, MD- June 9-12, 2007. R.Yuan, H. Li, H. Wang, M. Ochani, K. Ochani, J. Houston, M. Rosas, C.J. Czura, K.J. Tracey and H. Yang. Role of HMGB1 in apoptosis-mediated Sepsis lethality. Twenty -ninth Annual conference on Shock. Denver, Colorado, USA June 3-6, 2006V.A. Pavlov, M. Ochani, L. Yang, M. Gallowitsch Pureta, K. Ochani, X. Lin C.J. Czura, G. LaRosa, EJ M.iller, K.J. Tracey and Y. Al-Abed. Selective Alpha7 nicotinic receptor activation in1proves survival in murine sepsis. Poster accepted in FASEB 2006.M. Ochani, H. Liao, K. Ochani, H. Wang, KJ. Tracey & L. Ulloa, Cholinergic agonists in1prove survival in sepsis. Neuromod ulation Meeting abstract. L. Ulloa, H. Liao, M. Ochani, K. Ochani, J.M. Huston, C.J. Czura,& K.J. Tracey. Vagus nerve prevents systemic inflammation by inhibiting 1NF transcription in the spleen. Twenty -eight Annual conference on Shock. Marco Island, Florida June 4-7, 2005Al-Abed, L. Yang, H. Wang, M. Ochani, C. A. Camella, K. Ochani, M. Tanovic, M. Gallowitsch, V. A. Pavlov and K.J. Tracey. Selective alpha 7 nicotinic acetylcholine receptor agonist improves survival in a murine endotoxemia and sepsis. Twenty -eight Annual conference on Shock. Marco Island, Florida- June 4-7,2005V.A. Pavlov, M. Ochani, K. Ochani, H. Liao M. J M Huston, M. Gallowitsch Pureta, Y. Al-Abed, C.J. Czura, and K.J. Tracey. Cholinesterase inhibitors improve survival in a murine endotoxemia. Twenty -eight Annual conference on Shock. Marco Island, Florida- June 4-7, 2005H. Liao, M. Ochani, H. Wang, K. Ochani, J.M. Huston, C.J. Czura, E.J.Miller, K.J. Tracey & L.Ulloa. Cholinergic agonists inhibit HMGB1 release and improve survival in sepsis. Twenty -eight Annual conference on Shock. Marco Island, Forida- June 4-7, 2005V.A. Pavlov, M. Ochani, M. Gallowitsch Pureta, J M Huston, K. Ochani, Y. Al Abed, C.J.Czw-a and K.J. Tracey. Central but not peripheral muscarinic receptors modulate the cholinergic anti-inflammatory pathway. Accepted in FASEB 2005.J.M. Huston, M. Ochani, K. Ochani, M. Gallowitsch, V. Pavlov, L. Ulloa, C.J. Czura, and K.J. Tracey. The Cholinergic Anti-Inflammato1y Pathway is Independent of Other Vagus Nerve Fw1ctions. European Shock Society, 11th Congress 2005 Vienna, AustriaJ.M. Huston, M. Ochani, K. Ochani, M. Gallowitsch, V. Pavlov, L. Ulloa, C.J. Czura, and K.J. Tracey. The Cholinergic Anti-Inflammato1y Pathway is Independent of Other Vagus Nerve Functions. European Shock Society, 11th Congress 2005 Vienna, Austria. #214C.J. Czura, C. A. Amella, M. Ochani, M Gallowitsch, M. Tanovic, H. Wang, J.M. Huston, K. Ochani, H. Liao, S. Susarla, Y. Al-Abed, K. J. Tracey and L. Ulloa. Treatment of experimental sepsis with specific cholinergic agonist. European Shock Society, 11th Congress 2005 Vienna, Austria #216 C.J. Czura, J.M. Huston, M. Ochani, K. Ochani, V. Pavlov, C.N. Metz, and K.J. Tracey. Vagus Nerve Stimulation Attenuates Peripheral Hemorrhage in Mice. European Shock Society, 11th Congress 2005 Vienna, Austria C.J. Czura, C.A.Amella, M.Ochani, M gallowitsch, M. Tanovic, H. Wang, J.M. Huston, K. Ochani, H.Liao, S.Susarla, Y.Al-Abed, K.J.Tracey and L.Ulloa. Treatment of experimental sepsis with specific cholinergic agonist. European Shock Society, 11th Congress 2005 Vienna, AustriaJ.M. Huston, M.Ochani, K. Ochani, C.A. Amella, V.A. Pavlov, C. Metz C.J.Czura and K.J.Tracey. Vagus nerve stimulation attenuates bleeding in a rodent tail transection model. submitted to the Society of University Surgeons(SUS) Feb:05.J.M. Huston, M. Ochani, K. Ochani, C.A.Amella, V.Pavlov, C.N. Metz C.J.Czura and K.J.Tracey. Vagus nerve stimulation attenuates bleeding in a rodent tail transection model. Society of university surgeons, 66th annual meeting Nashville, Tennessee, 2005.J.M. Huston, M. Ochani, K. Ochani, C.J.Czura and K.J.Tracey. Vagus nerve stimulation using clinically approved parameters suppresses 1NF production in endotoxemic mice. 38th annual meeting of the association for Acadmedic surgery (AAS) Houston, TX Nov: 11-13,04.J.M. Huston, M. Ochani, K. Ochani, C.J. Czura, C.A. Amella, and K.J. Tracey. Mechanical stimulation of the vagus nerve is sufficient for activation of the cholinergic Anti-infalmmatory pathway in Mice. Twenty - Seventh Annual conference on Shock.Halifax, Nova Scotia -- June 5 - 8, 2004. C.A. Amelia, M. Ochani, K. Ochani, J.M. Huston, C.N. Metz, S. Varma, C.J. Czura and K.J. Tracey. Vagus nerve stimulation attenuates bleeding in a rodent tail transection model. Twenty - Seventh Annual conference on Shock.Halifax, Nova Scotia -- June 5 - 8, 2004.V.A. Pavlov, M. Ochani, M. Gallowitsch, K. Ochani, C.A. Amelia, J. Huston, C.J. Czura, Y. Al-Abed, and K.J. Tracey. Centrally acting acetylcholinesterase inhibitors in1prove survival in a murine model of sepsis. Twenty - Seventh Annual conference on Shock.Halifax, Nova Scotia -- June 5 - 8, 2004. V.A. Pavlov, M. Ochani, M. Gallowitsch, K. Ochani, C.J. Czura, S. lvanova, Y. Al-Abed, and K.J. Tracey. Suppression of peripheral inflammation through activation of brain muscarinic acetylcholine receptors. North Shore - LIJ Research institute 4th Annual Scientific Retreat (April 28 - 29, 2004). Mohonk Mountain House Lake Mohonk, New Paltz, NYV. A. Pavlov, S. Ivanova, M. Ochani, M. Gallowitsch, K. Ochani, C. A. Amella, Y. Al-Abed, L. Ulloa, H. Liao, CJ. Czura and K J. Tracey. Activation of brain muscarinic acetylcholine receptors suppresses peripheral inflammation. Experimental Biology April 17-April 21 2004 Washington, DC. Page 149, 836 H.Yang, s. Qin, A. kumar, M. Ochani, K. Ochani, C.A.Amelia, C.J.Czura, W.Newman, K.J. Tracey. Monoclonal HMGB1 antibodies protect against sepsis lethality in mice. 6th World congress on trauma, shock, inflammation and sepsis pathophysiology, immune consequences and therapy. March 2nd-March 6th, 2004, LMU Munich, Germany, Shock Vol.21, Page 128